Neurosurgery notes/Anatomy/Cerebellum/Intracerebellar nuclei

Intracerebellar nuclei

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General

  • Aka Roof nuclei (Close to the roof of 4th ventricle).
  • Intracerebellar nuclei act to modify muscular activity through the motor control areas of the brainstem and cerebral cortex.

Nuclei types

  • Dentate nucleus
    • Lies in the centre of each cerebellar hemisphere.
    • Cross-section through the nucleus shows a thin lamina of grey matter that is folded upon itself,
      • Resembles a crumpled purse with the hilum directed medially.
  • Emboliform and Globose nuclei lie medial to dentate nucleus.
    • These two nuclei are together called as nucleus Interposed in lower animals.
      • Interposed nuclei because they are interposed between the Fastigial and the dentate
  • Fastigial nucleus
    • Close to the midline
    • In the anterior part of the superior vermis.
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Nucleus
Afferent
Efferent
Functions
Fastigial nucleus
• Vestibular apparatus through the vestibular nerve
• Vestibulocerebellum, i.e. vermis and flocculonodular lobe
• To vestibular nuclei
• To reticular formation of the medulla
• To thalamus
• To midbrain (red nucleus, central grey matter— nucleus of Darkschewitsch)
• To visceral centres in brainstem
• To medial accessory and main inferior olivary nuclei
Control of muscle action (axial and proximal limb muscles) in response to labyrinthine stimuli
Emboliform and globose nuclei
(nucleus interpositus)
From the paravermal area or spinocerebellum
• To red nucleus
• To thalamus
• To reticular formation
• To pontine nuclei
• To dorsal accessory olivary nucleus
Controls crude movements of the limbs
Dentate nucleus
From neocerebellum or the lateral part of cerebellar hemisphere
• To thalamus
• To red nucleus
• To oculomotor nucleus
• To inferior olivary nucleus
• To reticular formation
Controls highly skilled voluntary movements of precision

Localisation of function

  • Projections pass to the cerebellar nuclei are arranged in a mediolateral sequence corresponding to the position of the nuclei.
    • Fastigial nucleus receives fibres from the vermis,
    • Globose and emboliform nuclei from paravermal regions,
    • Dentate nucleus from the lateral region
  • Visual and auditory input to
    • Primary visual area
      • Folium and tuber.
    • Secondary visual area
      • Biventral lobule and tonsil.
  • Vestibular impulses input to
    • Uvula
    • Nodule
    • Flocculus (vestibulocerebellum)
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