Liliequist membrane

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General

  • The Liliequist membrane is the arachnoid membrane separating the chiasmatic and interpeduncular cisterns.

Boundaries

  • Lower attachment:
    • Dorsum sellae
    • Posterior clinoid processes
  • Upper attachment: Mamillary body
  • Lateral attachment
    • The oculomotor nerves (CN III) course along the lateral wall of the interpeduncular cistern and form the pillars to which the leaves of Liliequist’s membrane often attach.

Has two components

  • Diencephalic membrane (Upper/anterior leaf)
    • Attachment/Boundary:
      • It extends upward and attaches to the floor of the third ventricle at the mamillary bodies.
    • Cistern Separation:
      • It separates the chiasmatic cistern (anteriorly) from the interpeduncular cistern (posteriorly).
    • Variability in Attachment:
      • Mamillary bodies
    • Structure:
      • It is typically the thicker of the two parts and is more frequently without perforations, allowing it to act as a more effective barrier to the passage of air or other substances through the subarachnoid space
  • Mesencephalic membrane (Caudal/posterior leaf)
    • Attachment/Boundary:
      • It extends backward and attaches along the junction of the midbrain and pons.
    • Cistern Separation:
      • It separates the interpeduncular cistern (anteriorly) from the prepontine cistern (posteriorly).
    • Contents:
      • The basilar artery passes through an opening in the mesencephalic membrane to enter the interpeduncular cistern.
    • Structure:
      • This membrane is highly variable; while some are thick with small perforations, most are thinner, often incomplete, and have larger perforations

Clinical significance

  • Aneurysms:
    • Aneurysms arising at the basilar apex may project into the diencephalic and mesencephalic leaves of Liliequist’s membrane.
  • Surgical Risk:
    • Five arachnoid membranes, including the diencephalic and mesencephalic membranes, converge on the oculomotor nerve; thus, traction on any of these membranes may rupture associated aneurysms.
  • Surgical Access:
    • Opening the diencephalic leaf of Liliequist’s membrane provides surgical access into the interpeduncular cistern
    • Opening the Sellar Segment is done to improve CSF flow during ETV.
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S: Sellar; D, Diencephalic; M, Mesencephalis
S: Sellar; D, Diencephalic; M, Mesencephalis
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