External Features
- Two ends (or poles)
- Narrow
- Anteriorly: interventricular foramen.
- broader
- Inferior and medially: superior colliculus
- separated from the geniculate bodies by the brachium of the superior colliculus.
Anterior
Posterior (Pulvinar)
- Four surfaces
- Lateral portion:
- Thalamocaudate groove
- Contains
- A bundle of efferent nerve fibres from amygdala called the stria terminalis
- Thalamostriate vein lie in this groove.
- Body of caudate nucleus
- Floor of the central part of the lateral ventricle formed by
- The lateral part of superior surface of thalamus AND
- The body of caudate nucleus
- Medial portion
- Separated from the ventricle by the fornix and by a fold of pia mater called the tela choroidea.
- Adjacent
- Hypothalamus
- Ventral thalamus
- The ventral thalamus separates the thalamus from the tegmentum of the midbrain
- Forms the greater part of the lateral wall of the 3rd ventricle
- Lined by ependyma
- Interconnected by interthalamic adhesion: a mass of grey matter
- inferior portion
- is separated from the hypothalamus by the hypothalamic sulcus.
- This sulcus runs from the interventricular foramen to the cerebral aqueduct
- At the junction of the medial and superior surfaces of the thalamus,
- Taenia thalami is present
- The ependyma of the third ventricle is reflected from the lateral wall to the roof.
- Underlying it there is a narrow bundle of fibres called the stria medullaris thalami (stria habenularis).
- Adjacent to internal capsule, which separates it from the lentiform nucleus
Superior
Inferior
Medial
Lateral
Internal structure
Consist of mainly grey matter and a small amount of white matter:
- White Matter
- Superiorly: covered by Strarum zonale: a thin layer of white matter
- Laterally: external medullary lamina: a thin layer of white matter
- Of note: medially it is covered by the ependyma of 3rd ventricle
- anterior group
- medial group
- lateral group
Outer surface
Internally a ‘Y’ shaped bundle of white matter called internal medullary lamina divides the grey matter of thalamus into three major groups of nuclei:
- Grey Matter
- Sensation from the face is received by which thalamic nucleus?
- Ventroposteromedial (VPM) nucleus.
- Ventroposterolateral (VPL) nucleus receives sensory input from the body
- Intralaminar nuclei
- Embedded within the internal medullary lamina.
- There are several nuclei in this group.
- Centromedian nucleus
- Most important
- Parafascicular nuclei
- Rostral intralaminar nuclei
- Midline nuclei
- consist of scattered cells that lie between the medial part of the thalamus and the ependyma of the third ventricle.
- Medial and lateral geniculate bodies (aka metathalamus)
Main thalamic nuclei
Other Thalamic Nuclei
graph LR A[Thalamus] --> B[Anterior] A --> C[Medial] A --> D[Lateral] B --> B1[Anterior nucleus] C --> C1[Medial dorsal nucleus] D --> D1[Dorsal group] D --> D2[Ventral group] D1 --> D1a[Lateral dorsal] D1 --> D1b[Lateral posterior] D1 --> D1c[Pulvinar] D2 --> D2a[Ventral anterior nucleus] D2 --> D2b[Ventral lateral nucleus] D2 --> D2c[Ventral posterior nucleus] D2c --> D2c1[Ventral posteromedial nucleus] D2c --> D2c2[Ventral posterolateral nucleus]
Connections of Thalamus
General
- The thalamus is the gateway to the cerebral cortex: all major sensory pathways, except olfactory, relay in the thalamus before ascending to the cortex.
Afferent
- From subcortical centres converge on the thalamus
Type of impulse | From | Through | To |
Exteroceptive impulses and proprioceptive impulses | ㅤ | Medial lemniscus, Spinothalamic tracts Trigeminothalamic tract. | Cerebellum, Cortex |
Visual impulses | Retina | Optic tract | Lateral geniculate bodies |
Auditory impulses | Cochlear | CN8 → lateral lemniscus/inferior colliculus | Medial geniculate bodies |
Sensations of taste | Tongue | CN12 → Solitariothalamic fibres | Primary somatosensory cortex. |
Olfactory impulses | Nasal mucosa | CN1 → Indirectly through amygdaloid complex (thalamus does not receive direct olfactory impulses) | Anterior olfactory nucleus, Piriformis cortex |
Visceral information | ㅤ | Reticular formation from the hypothalamus | ㅤ |
- From all parts of the cerebral cortex, the cerebellum, and the corpus striatum.
Efferent
Cerebral cortex
- Thalamocortical projections/radiations
- Form large bundles that are described as thalamic radiations/ thalamic peduncles
- Anterior (or frontal)
- Anterior nucleus and medial nucleus → frontal lobe
- Superior (or dorsal)
- Sensory motor → precentral and post central gyri
- Posterior (or caudal)
- Visual → calcarine cortex
- Inferior (or ventral)
- Auditory → heschl gyrus
Others
- Corpus striatum
- Hypothalamus
- Reticular formation