Neurosurgery notes/Anatomy/Peripheral nerves anatomy/Channels

Channels

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Peripheral nerves anatomy
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Acetylcholine
Glutamate
Dopamine
GABA
  • Move substances down their concentration gradient
  • 3 types
    • Ungated
      • Always open
      • e.g. K+-channel
    • Voltage-gated
      • Open in response to changes in membrane voltage
      • Na Channel
      • Ca Channel
    • Ligand-gated
        • Open in response to a ligand
        • e.g. post-synaptic membrane receptors
            • NMDA receptor
            Glutamate
            Gaba receptor
            GABA
            Nicotinic acetylcholine receptor
            Nicotine
        ChE Seminar Series: “Nicotinic Acetylcholine Receptors in Disease: from Structure to Therapeutic Strategies” Dr. José Lasalde (UPR-RP, VP Research and Technology) – UPRM Department of Chemical Engineering
    • Secondary messenger gated channels
        • Eg:
          • Cyclic AMP (e.g., beta-adrenoceptors, alpha2- adrenoceptors, M2 muscarinic AChR)
          • Inositol 1,4,5-triphosphate (e.g., alphal- adrenoceptors, Ml/M3 muscarinic ACIIR).
         
        A diagram of a cell AI-generated content may be incorrect.