Neurosurgery notes/Anatomy/White matter tracts/Association fibres/Central tegmental tract

Central tegmental tract

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Parent item
Association fibres
  • General
    • (CTT)
    • An extrapyramidal tract
    • Located bilaterally and symmetrically in the posterior part of the brainstem
  • Made up of
      • Part of the Guillain-Mollaret triangle (dentato-rubro-olivary system)
        • Afferent
          • Red nucleus
        • Efferent
          • Inferior olivary nucleus
      • Another small tract associated with the central tegmental tract
        • Afferent
          • Reticular nuclei
        • Efferent
          • Thalamus.
      The central tegmental tract is located in tegmentum pontis between the red nucleus and the inferior olivary nucleus.
       
  • Development
    • Myelination of CTT starts at approximately 9 months in fetal life and completes around the first year of age.
  • Clinical
    • Symmetric central tegmental tract hyperintensity (CTTH) is a pediatric brain MRI finding that has been associated with various disorders including epilepsy, cerebral palsy, antiepileptic medications, hypoxic-ischemic encephalopathy, neoplasms, and neurodevelopmental disorder