Neurosurgery notes/Basic science/Types of collagen

Types of collagen

View Details
logo
Parent item
Basic science
Collagen Type
Primary Locations
Associated Notes
Type I
Most common (90%)
Bone (osteoblast-derived), skin, tendon, dentin, fascia, cornea, late wound repair
Most common (≈90%). ↓ production in osteogenesis imperfecta type I (B-one)
Type II
Cartilage (including hyaline), vitreous body, nucleus pulposus
Type II = cartilage (cartwolage)
Type III
Reticulin—skin, blood vessels, uterus, fetal tissue, granulation tissue
Deficient in vascular type of Ehlers-Danlos syndrome (ThreE D)
Type IV
Basement membrane, basal lamina, lens
“Under the floor” (Four)—basement membrane. Defective in Alport syndrome; targeted by autoantibodies in Goodpasture syndrome