Frontal lobe epilepsies

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  • General
    • These types of seizures are usually short, occur more frequently during sleep, and tend to cluster.
    • Most patients report an initial aura of vague general body sensation or unspecified cephalic aura.
    • The patient initially may develop staring and behavioral arrest.
  • Numbers
    • Is the second most common localization-related epilepsy,
      • Accounting for 20-30% of surgical series.
  • Types
    • Jacksonian March.
      • Aka: sequential seizure
      • Focal seizure that starts primarily in the motor area and spreads,
      • Can lead to
        • LOC
        • Generalized tonic-clonic seizures.
      • Commonly begins in the hand and may involve the face early on.
        • Because the thumb and the mouth are situated near each other on the motor strip of the cerebral cortex.
    • Epilepsia Partialis Continua:
      • Persistent focal motor seizure activity affecting distal hand and foot muscles
      • A type of focal motor status epilepticus.
      • Seen in Rasmussen’s encephalitis
  • Lateralizing signs
    • Head version and unilateral clonic, tonic, or dystonic activity that correlate with contralateral onset.
  • Unless there is secondary generalization, responsiveness persists throughout the seizure.
    • Complex partial seizures of frontal lobe origin are characterized by partial or complete loss of consciousness.
  • Motor manifestations consist of prominent semi-purposeful automatism.
    • There are frequently bilateral and involve both legs and arms with features of running, pelvic thrusts, and bizarre behavior.
    • Upper extremity automatisms tend to be irregular, involving proximal muscles.
    • Later during the seizures laughing and crying may be observed.
    • Finally, hypermotor activity characterized by complex movements of the proximal segments of limbs and trunks may occur.
  • MRI Abnormalities
    • Encephalomalacia
    • Neoplasm
    • Vascular malformations
    • Cortical dysplasias
    • Migrational disorders.
  • In contrast,
    • Temporal lobe seizures
      • Have early and prominent oroalimentary automatism and repetitive upper extremity automatism involving mainly the distal segments.
      • Consciousness is more frequently affected or lost in temporal lobe epilepsy.