Neurosurgery notes/Functional/Seizure/Sudden Unexpected Death in Epilepsy (SUDEP)

Sudden Unexpected Death in Epilepsy (SUDEP)

View Details
logo
Parent item

Numbers

  • Overall rates of SUDEP in adults is 1 in 1000 and lower in children at 0.2-0.4 in 1000 per year.
    • In adults and children with medically intractable epilepsy rates are higher at 1 in 100-200 per year.

Cause of death

  • Is unclear but thought to be due to seizure related cardiac arrhythmias and/or respiratory compromise.

Risk factor

  • Severity of seizures
  • Frequency of seizures (particularly generalized tonic-clonic seizures)
  • Nocturnal seizures
  • Young adult
  • Poor adherence to treatment
  • Earlier age of seizure onset
  • Longer duration of epilepsy
  • Symptomatic epilepsy
  • Male gender