- Aspergillus fumigatus from the soil.
- It is named from its sporangia that resemble a container of holy water and only forms when growing with contact to air.
- Monomorphic septate hyphae that branch 45° acute angle
- Multiple haemorrhagic infarcts resulting from vasoinvasive Aspergillus arose in a child with severe combined immunodeficiency syndrome.
- Typical lesions are circumscribed, hemorrhagic, and softened.
- Numbers
- 3rd most frequent fungal CNS infection.
- Rarely diagnosed before death.
- May be associated with cerebral abscess in organ transplant patients
- Angioinvasive → hemorrhagic cerebritis and rarely meningitis.
- Treatment
- Amphotericin B + 5-fluorocytosine
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