Candidiasis

View Details
  • The most common fungal infection of the CNS,
  • Rarely diagnosed before autopsy.
  • Very rare in healthy individuals.
  • Candida albicans.
    • Most due to this
    • Normal flora of the GI tract, skin, and genitals.
  • Presents in the form of
    • Candidal meningitis
      • The most common CNS infection;
      • See ℞
    • Parenchymal infection
      • Candida brain abscesses are rare
    • Following ventricular shunt placement
      • Almost all fungal VP shunt infections are due to Candida spp.
  • Risk inc. w/
    • Antibiotics,
    • Steroids,
    • IV lines,
    • Diabetes mellitus,
    • Burns,
    • Immunosuppression,
    • IV drug abuse.
  • Forms multiple microabscesses with granulomas and rarely causes meningitis.
  • Infects the urine, blood, skin, heart, and lungs.
  • Treatment amphotericin B.