Neurosurgery notes/Infection/Cranial infection/TB Meningitis/Tuberculous vertebral osteomyelitis

Tuberculous vertebral osteomyelitis

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AKA

  • Tuberculous spondylitis,
  • Pott’s disease.

Location

  • Lower thoracic and upper lumbar levels.
  • Has a predilection for the vertebral body, sparing the posterior elements.
  • Psoas abscess is common (the psoas major muscle attaches to the bodies and intervertebral discs from T12–5).

Investigation

  • Radiology
    • Sclerosis of the involved vertebral body may occur.
  • Definitive diagnosis
    • Identification of acid-fast bacilli on culture or Gram stain of biopsy material (may be done percutaneously).

Clinical features

  • Typically symptomatic for many months.
  • Usually affects more than one level.
  • Neurologic deficit
    • In 10–47% of patients,
    • Due to
      • Medullary and radicular artery inflammation in most cases.
      • Neuronal Compression from
        • Epidural granulation tissue or fibrosis
        • Kyphotic bony deformity
          • The infection itself rarely extends into the spinal canal;

Management

  • Antibiotics
  • Surgery
    • The role of surgical debridement and fusion with TB is controversial, and good results may be obtained with either medical treatment or surgery.
    • Surgery may be more appropriate when definite cord compression is documented or for complications such as abscess or sinus formation or spinal instability.