Neurosurgery notes/Infection/Treatment for infection

Treatment for infection

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Parent item
Infection
Sub-item
Sepsis
  • What is C-reactive protein (CRP)? Where is it synthesized?
    • CRP is an acute phase reactant/plasma protein indicative of an acute inflammatory response.
    • CRP expression in the peripheral blood increases in response to injury or infection.
    • It is synthesized in the liver or adipocytes.
    • It is normal to have a mild rise of CRP after surgery;
    • This rise is highest on postoperative day 2 and subsides at postoperative day 5
  • Risk of C. Difficile infection varies by antibiotic
      • Frequently associated
      Occasionally associated
      Rarely associated
      Fluoroquinolones (e.g. ciprofloxacin)
      Macrolide (e.g. erythromycin)
      Metronidazole
      Clindamycin
      Trimethoprim
      Vancomycin
      Penicillins (broad-spectrum)
      Sulfonamide
      Aminoglycosides
      Cephalosporins (broad-spectrum)
      ㅤ
      Tetracyclines
      Carbapenems
      ㅤ
      Chloramphenicol