- AKA ADEM.
- Acute demyelinating condition, has been associated with relatively recent history of vaccination.
- Associated with
- Paramyxovirus
- Varicella
- Rubella
- Epstein-Barr virus
- Like MS, may also demonstrate oligoclonal bands in CSF.
- ADEM is generally monophasic, and lesions occur within a couple of weeks.
- CSF
- Raised prot
- Lymphocytic pleocytosis
- Treatment
- High-dose IV corticosteroids
- Good response
- Plasmapheresis
- IV immunoglobulin