Neurosurgery notes/Paediatrics/Developmental abnormalities/Intracranial Anomalies/Malformations of Cortical Development/Neuronal Migration and Organization Abnormalities/Microdysgenesis

Microdysgenesis

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Neuronal Migration and Organization Abnormalities
  • focally thickened cortex with disordered cryoarchitecture (large abnormally oriented neurons, hypertrophic astrocytes);
  • For example, cortical tubers (TSC); intractable epilepsy.