Neurosurgery notes/Paediatrics/Paediatric general

Paediatric general

Age ranges
  • newborn (ages 0–4 weeks)
  • Infant (ages 4 weeks – 1 year)
  • toddler(ages 1–2 years)
  • preschooler (ages 3–5 years)
  • school-aged child (ages 6–12 years)
  • adolescent (ages 13–19).
Average term newborn:
  • Weight is 3500 g
    • Abnormal
      • low birthweight is < 2500 g,
      • very low birthweight < 1500 g
      • extremely low < 1000 g
    • Neonates with birthweight below the 10th percentile are termed small for gestational age, and may be genetic or due to intrauterine growth restriction.
  • Height is 50 cm
  • OFC: 32.5-38 cm (mean 35 cm).
    • How to measure
      • Measuring tape should encircle the head and include an area 1-2 cm above the glabella anteriorly and the most prominent portion of the occiput posteriorly.
    • Head circumference increases approximately
      • By 2 cm in first month
      • By 6 cm in the first 4 months
      • Approximately 1 cm/month during the first year of life
      • Brain weight doubles by 4-6 months of age and triples by 1 year of age
      • The majority of head growth is complete by 4 years of age
    • Measurement of OFC in the newborn may be unreliable until the 3rd or 4th day of life since it may be affected by
      • Caput succedaneum
      • Cephalohematoma
      • Molding
    • It may be inappropriate to use a single head circumference standard for children in all countries or ethnic groups.
    • The standard growth curves are not appropriate for monitoring the head size of children with certain medical conditions associated with
      • macrocephaly (e.g. achondroplasia, neurofibromatosis) and other curves are available for these specific conditions.
  • The circulating blood volume of a premature neonate is approximately 80 ml/kg
    • If loss 10 % need to start transfusing
Gastrulation (notochordal integration)
Gastrulation (segmental notochordal formation)
Primary neurulation
Secondary neurulation
Ventral induction
Neural proliferation
Neuronal migration
Myelination
Dorsal enteric fistula
Segmentation defects
Myelomeningocele
Lipoma of filum terminale (fatty filum)/conus
Holoprosencephaly
Microencephaly
Lissencephaly
Adrenoleukodystrophy
Split cord malformation
Indeterminate/block vertebrae
Myelocele
Tight filum terminale
Septo-optic dysplasia
Macroencephaly
Heterotopia
Metachromatic leukodystrophy
Neurenteric cyst
Caudal regression syndrome
Lipomyelomeningocele
Persistent terminal ventricle
Pituitary anomalies
Neurocutaneous syndromes
Pachygyria
Pelizaeus-Merzbacher disease
Dermal sinus*
Segmental spinal dysgenesis
Lipomyelocele
Terminal myelocystocele
Inferior cerebellar vermis hypoplasia
Aqueduct stenosis
Schizencephaly
Intradural lipoma
Dandy-Walker spectrum
Polymicrogyria
Dermal sinus*
Mega cisterna magna
Agenesis of corpus callosum
Rhombencephalosynapsis
Joubert syndrome