General
- Tool
- Pin movement is proportional to clot strength
- Clot grows → pin moves more
- Clot breakdown → pin moves
- Takes 45-60 mins to get results (life cycle of a clot)
3 phases
Clot initiation
- Reaction time (R Time)
- Time to the first sign of clot formation
- Depends on
- Clotting factors
- Anticoagulants
- Normal: 5-10 mins
- If prolonged
- Reverse anticoagulants
- FFP
- Kinetics (K)
- Time from the end of R until the clot reaches 20mm
- Reflects speed of initial clot formation
- Aka Fibrinogen function
- Normal: 1-3 mins
- If prolonged give Cryoprecipitate
- Alpha angle
- Angle tangent to the curve at K
- Rate of clot formation
- Rate of fibrin formation and cross linking
- Aka Fibrinogen function
- Normal 54-80 degree
- If prolonged give
- Cryoprecipitate
Clot strength
- Maximum amplitude (MA)
- Normal: 55-73mm
- Depends
- Platelets
- Fibrin
- Factors II and III
- If low give
- Platelets
- DDAVP
Clot stability
- Clot breakdown
- Lysis time (LY30)
- Percent of clot lysis 30 mins after MA
- Normal 0-9%
- Increased give
- TXA
Made with Bullet