ITB infection

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  • Incidence of infection
    • Variable with rates of 3.2–27.5%
    • Higher risk in
      • Paeds
      • Patient requiring ITB for management of severe spasticity compared
      • Patient with increased risk for comorbidities such as microbial contamination from neurogenic bladder, decubitus ulcers, tracheotomies, and feeding tubes.
    • Some evidence that the rates of infection are decreasing due to
      • Use of a subfascial implant technique
      • Improvements in presurgical prophylaxis
  • Two types of infections:
    • Superficial infection
      • Eg: seromas and cellulitis
      • Oral antibiotics (typically covering gram-positive bacteria) and without the need for explantation.
    • Deeper, advancing infections.
      • Broad spectrum IV antibiotics (such as cefazolin, clindamycin, or vancomycin)
      • Explantation
        • Pump rate should be titrated down more than 48–72 hours before explant to minimize the risk of ITB withdrawal while treating with antibiotics, unless the infection is life-threatening.
        • Oral or IV antispasmodic supplementation should proceed as described in the underdosing section previously.
  • The highest risk for infection typically occurs in the immediate perioperative phase.
  • Consultation with infectious diseases specialists may be warranted to determine the scope and duration of antimicrobial therapy.