Peripheral nerve stimulation of pain

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Peripheral nerve stimulation

  • Indicated
    • Refractory severe chronic,
    • Focal neuropathic pain
      • Post-traumatic neuropathy,
      • Complex regional pain syndromes,
      • Post-herpetic neuralgia affecting 1 or 2 dermatomes
  • Technique
    • Placement of a stimulating electrode over a named peripheral nerve to elicit paresthesias along the innervated territory (e.g. occipital, supraorbital, infraorbital, radial, ulnar, median, tibial, peroneal, and sciatic nerves).

Peripheral nerve field stimulation (PNfS)

  • Aka
    • Subcutaneous neurostimulation
    • Targeted subcutaneous stimulation
  • Technique
    • Involves positioning of one or more electrodes within the region of maximal pain, where small distal branches of nerves are targeted within the subcutaneous space.
      • Field stimulation produces paresthesias along a diffuse painful area that may not correlate with one specific peripheral nerve territory.
    • Body regions rather than nerves are used to describe the PNfS (e.g. low back, trunk, joint).
  • “Hybrid” stimulation
    • Aka
      • Spinal-peripheral neurostimulation
      • Triangular stimulation.
    • = Spinal cord stimulation (SCS) + PNfS
    • Shown to achieve broader coverage of axial back pain than either SCS or PNfS individually.
  • Complications
    • Infection,
    • Lead erosion,
    • Migration of the lead,
    • Mechanical issues with the device.
    • Pain at the site of the generator or lead site occurs in some patients.