Anterior instrumented fusion for AIS

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Indications

  • Suitable for single thoracic and lumbar deformities with flexible compensatory curves, specifically
    • Lenke type 1 curvatures
      • Degree of Scoliosis:
        • Surgical correction is indicated with a Cobb angle of 40 to 50 degrees.
      • It is ideal for single thoracic curves (Lenke type 1 A–C) with pronounced hypokyphosis (T5–12 sagittal modifier—or N).
        • However, it should not be applied in primarily hyperkyphotic cases (which are rare).
    • Lenke type 5 curvatures
      • Degree of Scoliosis:
        • Surgical correction is indicated with an angle of 35 to 40 degrees.
  • Patient Age:
    • It is generally not recommended for very young children who tend to develop hyperkyphosis during further growth due to the anterior tethering effect of the procedure.
  • Other Factors:
    • The decision also depends on the age of the patient, the expected further progression, and the cosmetic impairment (such as a rib hump).

Advantages (Pros)

  • Correction and Derotation:
    • Achieves complete correction of the deformity in all three planes with high construct stability.
      • Provides excellent results in coronal plane correction.
      • Is superior in the restoration of the sagittal profile and apical derotation.
    • Derotation is more effective in Lenke type 5 curves.
      • Allows for powerful derotation of the apical vertebrae in thoracolumbar/lumbar curves.
    • Offers excellent rib hump correction, which has been shown to be better than posterior correction procedures.
  • Fusion Length:
    • Fusion is shorter compared to posterior correction, which is a significant advantage, especially in lumbar segments.
      • To preserve mobility and distribute loads, potentially
        • Reducing early disc degeneration in remaining mobile segments.
        • Reduce low back pain
      • in Anterior thoracic fusion plan will be to fuse from End to End vertebrae; In posterior approaches plan will be to fuse from Stable to stable vertebrae
  • Stability and Outcomes:
    • High stability of the construct.
      • Maintains thoracic curve correction, leading to stable spontaneous correction of the second lumbar curve over time.
    • The pseudarthrosis rate decreased with improved techniques.
  • Physiological Restoration:
    • Can correct hypokyphosis and restore a physiological sagittal profile.
    • An aggressive anterior release with shortening of the anterior column can lead to spontaneous correction of scoliosis and restoration of thoracic kyphosis.

Disadvantages (Cons)

  • Pulmonary Function:
    • Pulmonary function is impaired postoperatively due to the opening of the chest wall.
    • However, pulmonary function recovers within a few months to two years, becoming comparable to preoperative values.
  • Hyperkyphosis Risk:
    • Since the anterior correction is kyphogenic (shortens the anterior column), it should not be applied in primarily hyperkyphotic cases.
    • There is a risk of developing hyperkyphosis during further growth in very young patients with high growth potential.
  • Surgical Morbidity (for Thoracoscopic approach):
    • While video-assisted thoracoscopic surgery aimed for reduced morbidity, some studies found blood loss and operation time to be equal or even higher compared to open thoracotomy.
  • Potential for Degenerative Disc Disease:
    • While aiming for shorter fusion, the stress on the remaining mobile segments might be higher, which may result in an increased rate of degenerative disc disease over a lifetime.

General Principles

Thoracic Curves (Lenke Type 1)

  • Fusion Extent:
    • Correction and fusion are typically performed from end vertebra to end vertebra.
      • For common Lenke 1 curves,
        • The uppermost instrumented vertebra is T5 or T6,
        • The lowest instrumented vertebra is T11, T12, or L1.
  • Patient Positioning:
    • The patient is placed on a hinged table (with the hinge at the curve's apex) in the lateral position, with the convexity of the curve facing upwards.
  • Surgical Approach:
    • A single skin incision is made.
    • A double thoracotomy is performed:
        • the upper incision is usually between the 4th and 5th or 5th and 6th ribs, with distal osteotomy of the rib.
        • The lower incision is typically four rib spaces lower
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    • This approach provides unobstructed access to the disc spaces and a clear view of the posterior ligaments.
  • Disc and Rib Management:
    • Rib heads overlapping the discs are removed.
    • Depending on the severity of the rib hump, the proximal parts of the ribs may be resected.
    • Discs are completely removed, including the contralateral and posterior annulus, to achieve sufficient segmental mobility for correction.
    • In very rigid cases, the longitudinal fibres of the posterior longitudinal ligament should be partially disrupted by distraction.
    • Removal of discs shortens the anterior column of the spine, which helps restore a physiological thoracic kyphosis.
    • In severe hypokyphosis, the convex and anterior parts of the endplates should also be removed to reinforce the kyphotic effect.
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  • Screw Insertion:
    • Screws are inserted into the centre of the vertebral body.
    • They are placed parallel to the endplates and, accounting for the rotation of each vertebra, parallel to the posterior wall.
  • Correction Manoeuvres:
    • Initial correction is achieved by setting the operating room table back to a neutral position and applying traction to the patient.
    • The rod is pre-bent to match the intended sagittal contour.
    • Further correction is achieved through a
      • Cantilever technique
      • Rotation of the pre-bent rod from scoliosis to kyphosis
      • Final compression.
  • Grafting:
    • A structural graft or cage may be used at the lowest fused disc space to prevent junctional thoracolumbar kyphosis.

Lumbar Curves (Lenke Type 5)

  • Fusion Extent:
    • Correction and fusion are also typically performed from end vertebra to end vertebra, commonly from T11 to L3.
  • Surgical Approach:
    • The approach used is a thoracic-phrenic-lumbotomy, which involves sectioning of the diaphragm close to the costal insertion.
  • Disc and Screw Management:
    • After resection of the discs, screws are inserted.
  • Correction and Stabilisation:
    • A pre-bent rod (contoured for the intended sagittal profile) is inserted.
    • Correction is achieved using a cantilever technique during rod insertion and by rotation of the pre-bent rod from scoliosis to lordosis.
    • Structural spacers (e.g., cages) are inserted into the debrided disc spaces.
    • Compression is applied via the rod.
    • Autologous bone or bone substitutes are added for bony fusion.
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Instrumentation

  • Fixation can be performed with single or double rod instrumentation, as follow-up studies have shown no significant difference in outcomes between them.

Postoperative Care

  • Patients are typically mobilised on the first postoperative day.
  • A brace is not necessary.
  • Patients are allowed to begin well-controlled sports (e.g., jogging, swimming, bicycling) three months after surgery.
  • Full activity may be resumed six months after surgery.