- Technetium agents based on the technetium-99m (Tc-99m) radioisotope are frequently used agents in medical imaging.
- A radiopharmaceutical labelled with Tc-99m constitutes a co-ordination complex in which ligands bond to a central atom of Tc-99m by co-ordinate covalent bonds
- Radioactive technetium radiotracer can be chelated to a number of different compounds to create specific radiopharmaceuticals
- Tc-99m HMPAO labelled WBC: infection scintigraphy
- High false positive rate for infection
- Early diagnosis of pyogenic vertebral osteomyelitis because it demonstrates positive findings before X-ray changes
- Tc-99m HMPAO (hexamethylpropyleneamine oxime)
- Ictal and interictal seizure foci investigation
- Technetium-99m ECD: CNS imaging
- Technetium-99m GHA
- Oncological imaging (e.g. low-grade glioma, lung)