Ankylosing diseases

DISH
Ankylosing spondylitis
Syndesmophytes
Nonmarginal
Marginal
Radiographs
"Flowing candle wax"
"Bamboo spine", squaring of vertebral bodies, "shiny corners" at attachment of annulus fibrosus (Romanus lesions)
Disc space
Preservation of disc space
AS in cervical spine will show ossification of disc
space
Osteopenia
No osteopenia (rather, there may be increased radiodensity)
Osteopenia present
HLA
No evidence of association with HLA-B27. Associated with HLA-B8 (common in patients with DISH and diabetes)
Strong association with HLA-B27
Age group
Older patients (middle aged)
Younger patients
SI joint involvement
No involvement (SI joint abnormality generally excludes diagnosis of DISH)
Bilateral sacroiliitis
Diabetes
Yes
No