Neurosurgery notes/Tumours/Germ cell tumours/Non germinomas/Immature teratoma

Immature teratoma

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Status
Done
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Parent item
Non germinomas

Definition

  • A germ cell tumour composed of somatic tissues derived from two or three of the germ layers (i.e. the ectoderm, endoderm, and mesoderm).
  • If there is any evidence of incomplete differentiation for any element

Frequency

  • 19.6% (23.3% of Teratoma)

Histopathology

  • Macroscopic
      • Incompletely differentiated elements
      • Contain immature, embryonic, or fetal tissues either exclusively or in addition to mature tissues
       
      Large immature teratoma of the cerebellum in a 4-week-old infant, with characteristic cysts and chondroid nodules.
      Large immature teratoma of the cerebellum in a 4-week-old infant, with characteristic cysts and chondroid nodules.

Blood markers

  • Alpha-fetoprotein